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Image Search Results
Journal: Molecular Metabolism
Article Title: Effects of a long-acting secretin peptide analog alone and in combination with a GLP-1R agonist in a diet-induced obesity mouse model
doi: 10.1016/j.molmet.2023.101765
Figure Lengend Snippet: In vitro potency and lipolysis assay of BI-3434 and native secretin. Representative concentration-response curves showing cAMP accumulation in cells stably expressing human SCTR after activation with human secretin (A) and BI-3434 (B). Summary of EC 50 values for tested compounds (C), refers to A and B. Dose-response curves showing the glycerol levels of differentiated murine adipocytes treated with native secretin, BI-3434, and isoproterenol (D). Summary of EC 50 values for tested compounds (E), refers to D.
Article Snippet: Cells were differentiated into
Techniques: In Vitro, Concentration Assay, Stable Transfection, Expressing, Activation Assay